Mifepristone (RU-486) plus Progesterone

 

RU-486 plus progesterone more effective than either alone vs. breast cancer
MCF-7 cell apoptosis and cell cycle arrest: non-genomic effects of progesterone and mifepristone (RU-486) and uterine cancer cell lines (2010)

RU-486 plus progesterone more effective than either alone vs. prostate cancer
Induction of apoptosis by mifepristone and tamoxifen in human LNCaP prostate cancer cells in culture. (2000)

Estradiol prevents RU-486 from killing prostate cancer cells
Influence of Estrogen and Polyamines on Mifepristone-induced Apoptosis in Prostate Cancer Cells (2004)

RU-486 by itself is effective against breast, prostate, bone, and ovarian cancer
Antiprogestin mifepristone inhibits the growth of cancer cells of reproductive and non-reproductive origin regardless of progesterone receptor expression (2011)

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Contact info: ed@math.uchicago.edu